微量量热法研究草乌生物碱对细菌的代谢作用

STUDY ON THE BACTERIOSTASIC ACTIVITY OF RADIX ACONITI FERI BY MICROCALORIMETRY

从草乌中提取生物碱 ,用瑞典产的 2 2 77型热活性检测仪测定了不同浓度的草乌生物碱液对大肠杆菌和金黄色葡萄球菌代谢作用的热功率—时间曲线 ,计算出细菌生长的速率常数 ,建立了速率常数与药物浓度间的关系 ,进而确定了最佳浓度 .

Alkaloids were extracted from Radix Aconiti Feri. By using 2277 Thermal Activity Monitor (Sweden), bacteriostasic activity of different concentration solution of Radix Aconiti Feri for E.coli and S.aureus was determined, the growth rate constants were calculated, the relationship of -C and the optimum allowable concentrations were established.