上皮性卵巢癌内微血管密度的意义

The relationship between microvascular density and clinicopathologic study in Primary Epithelial ovarin carcinomas

目的探讨 34例上皮性卵巢癌内微血管密度 (MVD)的病理意义。方法应用免疫组化SP法对 34例上皮性卵巢癌内微血管密度 (MVD)进行检测。结果上皮性卵巢癌内MVD与网膜或腹股沟淋巴结转移相关 (P <0 0 5 ) ,FIGO分期中Ⅰ、Ⅱ期患者的MVD显著低于Ⅲ、Ⅳ期患者 (P <0 0 5 ) ,MVD与组织学分级无关 (P >0 0 5 )。结论上皮性卵巢癌内MVD与患者的淋巴结转移及FIGO分期有关。

Objective To study the relationship between microvascular density(MVD) and clinicopathologic in 34 cases of Primary Epithelial ovarin carcinomas. Methods The MVD in 34 cases of Primary Epithelial ovarin carcinomas were studied by immunohistochemistry of SP. Results The MVD was correlated significantly with Lymph node metastasis ( P <0 05),The MVD of tumor in stage Ⅰ?Ⅱ were significantly lower than that of tumor with stage Ⅲ?Ⅳ( P <0 05).In addition,the MVD was not related with diffeentiation( P >0 05). Conclusion The high expression of MVD was correlated significantly with biological findings.