急性胆管炎病人血清α-谷胱甘肽-S-转移酶的检测及意义

Detecting and its significance of serum α-glutathione-S-transferase in patients of acute cholangitis

[目的 ]探讨血清α 谷胱甘肽 S 转移酶 (α GST)在急性胆管炎病人肝功能异常检测中的临床应用价值 .[方法 ]实验组为 32例急性胆管炎病人 ,对照组为 2 0例健康志愿者 .α GST检测采用酶联免疫法 ,谷丙转氨酶、谷草转氨酶检测采用常规生物化学方法 .[结果 ]急性胆管炎病人血清α GST升高 ,发病早期α GST升高快于谷丙转氨酶、谷草转氨酶 ,经治疗后α GST下降快于谷丙转氨酶、谷草转氨酶 .[结论 ]α

OBJECTIVETo study the value of clinic application of detecting the serum α-glutathione-S-transferase (α-GST) as a marker of liver function in patients of acute cholangitis.METHODSThe experimental group includes 32 patients of acute cholangitis and control group includes 20 healthy volunteers. α-GST was detected by enzyme immunoassay(EIA) and ALT and AST by routine biochemistry methods.RESULTSThe α-GST was increased in patients of acute cholangitis, the increase of α-GST was faster than ATL and AST in early stage and drops faster than ALT and AST after treatment.CONCLUSIONα-GST is a more sensitive marker of liver function.