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多发性硬化发病机制中异常T细胞迁徙的研究进展 被引量:2

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摘要 多发性硬化 (multiplesclrosis ,MS)是中枢神经系统一种广泛脱髓鞘性自身免疫性疾病。它的发病机制是遗传、免疫和环境共同作用的结果 ,其机制涉及自身髓磷脂蛋白 (MBP)反应性T细胞异常活化后 ,对中枢神经组织的浸润和破坏。近年来 ,MS病程中外周血淋巴细胞的异常迁徙使人们对其细胞表面趋化因子、趋化因子受体和粘附分子的表达情况产生了兴趣。
作者 林泓怡
出处 《国外医学(免疫学分册)》 2003年第1期7-10,共4页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
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同被引文献30

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