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白血病细胞JAK/STAT途径异常激活 被引量:2

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摘要 JAK STAT信号通路主要包括JAK和STAT两大家族。JAK家族是细胞内一组蛋白酪氨酸激酶 ,主要参与造血因子受体超家族导导的信号转导。STAT家族是一组极为重要的转录因子。JAK STAT途径的异常活化可引起细胞的表型改变和恶性转化 ,针对JAK
出处 《国外医学(生理病理科学与临床分册)》 2002年第6期568-570,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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