降纤酶联合尼莫地平治疗急性脑梗塞疗效观察

Clinical Analysis of the eflect of Acute cerbral infarction Treated by Defibrase and Nimodipine

目的 观察降纤酶合尼莫地平治疗急性脑梗塞的临床疗效及相关生化指标 ,探讨降纤抗栓复流和脑保护在急性脑梗塞治疗中的必要性。方法 对符合条件的病例随机分 2组 ,治疗组予降纤酶加尼莫地平治疗 ,对照组予血栓通加胞二磷胆碱治疗 ,分别对其疗效 ,血液流变学 ,凝血酶原时间进行比较。结果 治疗组临床疗效及血流变学指标改善明显 ,且无增加副作用。结论 降纤酶有降纤抗凝溶栓作用 ,尼莫地平抑制Ca2 + 内流保护脑细胞 ,同时有改善血液流变性 ,两药联合应用治疗急性脑梗塞有协同作用 。

Objective: To evaluate the eflect of defibrase and Nimodipine on the acute infarction.Methods: All patient were devided into two groups by random.A group were injected defidrase and Nimodipine.B group were injected cilicoline and Xue Suan Tong to compared the effect of A and B in the scores of neurological function deficits.the marks of hemorrheology and prothrombin.Results: The scores of neurological function deficits and the marrs of hemorrheolpgy of the patients with defibrase and Nimodipine treated were improved.Conclusion: There is the collaborative effect that defibrase and Nimodipine treat the Acute cerebral infaretino.