磁共振胆胰管成像联合肿瘤标记物CA19-9在胆管癌诊断中的价值

Value of Magnetic Resonance Cholangiopancreatography Associate with CA19-9 for Diagnosis of Cholangiocarcinoma

目的 探讨磁共振胆胰管成像 (MRCP)联合肿瘤标记物CA19- 9在胆管癌中的诊断价值 .方法 回顾性分析 2 6例手术及病理证实为胆管癌和 2 2例胆道良性疾病病人的术前MRCP影像特点 ,并结合血清肿瘤标记物CA19- 9的检测进行评价 .结果 MRCP诊断的敏感性为 88% ,特异性为 84% ,阳性预测值为 85 % ,阳性似然比为 5 5 ;CA19- 9的敏感性为 82 % ,特异性为 79% ,阳性预测值为 84% ,阳性似然比为 3 9.联合诊断的敏感性为 92 % ,特异性为 88% ,阳性预测值为 96% ,阳性似然比为 7 7.结论 MRCP联合血清CA19- 9的检测 。

Objective To evaluate the value of magnetic resonance cholangiopancreatography(MRCP) associated with CA19-9 for diagnosis of cholangiocarcinoma.Methods Retrospective analysis behavior of MRCP in 22 patients with benign biliary tract disease and 26 patients with cholangiocarcinoma conformed by laparotomy and pathology examination,CA19-9 was detected too. Result Sensitivity,specificity,positive predictive value and positive likelihood ratio was 88%,84%,85% and 5 5 in MRCP;82%,79%,84% and 3 9 in CA-199;92%,88%,96% and 7 7 in MRCP associated with CA19-9.Conclusions These recults suggest that the use of MRCP associated with CA-199 can help the diagnosis of cholangiocarcinoma.