幽门螺杆菌相关性疣性胃炎患者症状及胃动力关系

Correlation of Helicobacter pylori infection with symptoms and gastric motility in verruciform gastritis

目的 探讨幽门螺杆菌 (HP)感染与疣状胃炎患者病理改变 ,临床症状及胃动力改变的相关性。方法 对 36例HP阳性及 32例HP阴性患者的胃黏膜炎症程度、临床症状进行评分 ,依靠病情 0～ 3分 ,症状频率 0～ 3,将临床症状分为 5种 ,并进行胃动力检查。结果 两组患者胃黏膜炎症程度及胃动力改变存在显著性差异 (P <0 .0 1或0 .0 5 ) ,而总的临床症状评分在两组间无明显差异 ,但HP阳性组的腹痛症状评分比HP阴性组的差异有显著性 (P <0 .0 1)。结论 HP感染对疣状炎患者临床表现 (疼痛 )、胃黏膜炎症程度及胃动力有影响。

Objective To investigate correlation of Helicobacter pylori (HP) infection with pathological changes,clinical symptoms and gastric motility changes in verruciform gastritis patients.Methods Sixty eight patients were comfirmed by gastroscopy and pathology examinations.Of them,36 HP positive(HP+) and 32 negative(HP-).The gastric mucosa inflammatory degree was judged by pathology.Five clinical symptoms were scored according to severity(0 3) and frequency(0 3),including abdominal bloating,abdominal pain,nausea,vomiting,and so on.The chart of gastric motility was recorded by before and 30 miniutes after a test meal.Results A close correlation was shown between both groups in the gastric mucosa inflammatory degree and gastric motility (P< 0.01 or 0.05 ).The total symptom score was no significant differene between the two groups,while the score of abdominal pain in HP+ group was significantly higher than that in HP-group (P< 0.01 ).Conclusion HP infection has some influence on clinical manifestations(pain),motility and mucous inflammation of verruciform gastritis.