68例肺癌骨转移部位的分析

CLINICAL ANALYSIS FOR THE METASTASIS SITES OF 68 CASES WITH LUNG CANCER

目的 探讨肺癌骨转移的临床特点。方法 临床资料回顾性分析。结果 肺癌骨转移多发者占 81.8% ,单发者 18.2 %。肺癌患者中腺癌发生骨转移占 6 5 .75 % ,鳞癌 34.2 1% ,小细胞未分化癌 38.89%。骨转移的部位胸部 6 6 .18% ,脊柱 5 2 .94% ,骨盆 42 .6 4% ,四肢 30 .88% ,头颅 2 0 .5 9%。腺癌以肋骨、脊柱、骨盆转移为主 ,鳞癌及小细胞肺癌以胸部和脊柱转移为主。X线、CT、MRI检查提示骨转移以溶骨性骨破坏的占 82 .35 % ,成骨性骨破坏11.76 % ,混合性损害 5 .88%。结论 肺癌骨转移以多发性、溶骨性骨破坏为特征。腺癌骨转移发生率最高 ,其次为小细胞癌及鳞癌。

Objective To describe features of osseous metastases in patients with lung cancer.Methods 68 cases were retrospectively analysed. Results 81.8% patients had multiple osseous metastases and 18.2% had single metastasis.In all the 68 cases,65.75% was adenocarcinoma,34.21% squamous carcinoma,38.89% small cell lung cancer. The frequencies of metastasis sites were as follows,eg, ribs(66.18%),thoracic and lumber vertebrae(52.94%),pelvis (42.64%),limbs(30.88%).Adenocarcinoma was prone to metastasize to thoracic vertebrae and pelvis,squamous carcinoma and small cell lung cancer to ribs and thoracic vertebrae . In patients undergoing X-ray?CT?MRI examination,82.35% had osteolytic damages,11.76% osteoblastic damages,5.88% mixed damages.Conclusions Osseous metastasis in patients with lung cancer is characterized by multiple osteolytic damages. Adenocarcinoma is one of the most common types of lung cancer that causes osseous metastasis.=