新生儿病毒及支原体肺炎的病原学分布

Etiological constituent of viral and mycoplasmal pneumonia of neonates

目的:了解本地区新生儿病毒及支原体肺炎的病原学分布。方法:采用免疫酶法(ELISA)检测肺炎患儿血中8型常见病毒及支原体特异性 IgM。结果:肺炎组111份血清中,特异性 IgM 检测阳性40份(36.04%);对照组30份血清检测均阴性。40份阳性血清中,8型病毒及支原体 IgM 检测阳性50例次,其中 RSV1例(0.9%),ADV_317例(15.3%),ADV_71例(0.9%),PIV4例(3.6%),CoxB5例(4.5%),ECHO10例(9.0%),CMV7例(6.3%),MP5例(4.5%),HSV_1未检出;33份(29.7%)检测出1种特异性 IgM,7份(6.3%)检测出2种或2种以上特异性 IgM。结论:病毒及支原体为本地区新生儿肺炎的重要病原,南方的病原学分布与北方不同,多种病原可混合感染。

Objective:To explore etiological constituent of viral and mycoplasmal pneumonia of neo- nates in Chengdu district.Methods:8 type viral and mycoplasmal special serum IgM were detected by enzyme linked immunosorbent assay(ELISA) in infants with infectious pneumonia.Results:There were positive special serum IgM in 40 cases(36.04%)of 111 infants with pneumonias.30 infants as control were negetive serum IgM.There were 50 consisting of 8 type viral and mycoplasmal special IgM in the above 40 infants with positive serum results.Among 50,1(0.9%)was RSV,17(15.3 %)were ADV_3, 1(0.9%)ADV_7,4(3.6%) PIV,5(4.5%) CoxB,10(9.0%) ECHO,7(6.3%)CMV,5(4.5%) MP,while HSV_1 infection was not exit.In 40 infants with positive serum IgM 33(29.7%) were only de- tected one kind of IgM and 7(6.3%)were two and more kinds of IgM.Conclusion:Viruses and myco- plasma are important pathogens of neonatal pneumonia in Chengdu district.Etiological constituent of neo- natal pneumonia in the south is different from that of the north.Infants with pneumonia can be infected by several kind of pathogens simultaneously.