复方熟地胶囊治疗青春期功能失调性子宫出血60例疗效观察

Treatment of Hebetic Dysfunctional Uterine Bleeding by Fufang Shudi Capsule:A Clinical Observation of 60 Cases

目的:观察复方熟地胶囊对青春期功能失调性子宫出血的临床疗效。方法:将90例青春期功血患者随机分为2组,治疗组60例根据月经周期分别以复方熟地胶囊1号(熟地黄、菟丝子、薏苡仁、续断、旱莲草、女贞子、淫羊藿、山茱萸、山药、白芍)和复方熟地胶囊2号(上方加益母草、炒蒲黄、炒五灵脂、紫草)治疗;对照组以己烯雌酚、安宫黄体酮治疗。结果:总有效率治疗组为85.0%,对照组为73.3%,2组总有效率比较,差异无显著性意义(P>0.05);3天内血止治疗组19例(31.7%),对照组6例(20.0%),2组差异无显著性意义(P>0.05)。半年后随访,复发率治疗组为9.7%,对照组为52.9%,对照组明显高于治疗组(P<0.005)。结论:复方熟地胶囊对青春期功能失调性子宫出血具有较好的治疗优势,既有调经止血作用,也有促排卵作用,且远期疗效巩固。

Objective:To observe the clinical effect of Fufang Shudi Capsule (FSC) for hebetic dysfunctional uterine bleeding (HDUB).Methods:90 cases of HDUB were allocated to two groups randomly.Treatment group (60 cases) treated by No.1 FSC (including Radix Rehmanniae Preparata,Semen Cuscutae,Semen Coicis,Radix Dipsaci,Herba Ecliptae,Fructus Ligustri Lucidi,Herba Epimedii,Fructus Corni,Rhizoma Dioscoreae and Radix Paeoniae Alba) and No.2 FSC(including No.1 FSC added with Herba Leonuri,Pollen Typhae (fried),Faeces Trogopterori (fried) and Radix Arnebiae seu Lithospermi) accordingly.The control group treated by stilbestrol and provera.Results:The total effective rate was 85.0%and 73.3%respectively in treatment and control groups. The short-term curative effect was similar in two groups (P > 0.05).Hemastasis within 3 days occurred in 19 cases (31.7%) of treatment group and 6 cases (23.1%) of control group (P > 0.05).A half-year follow-up revealed a recurrence rate of 9.7%and 52.9%respectively (P < 0.01).Conclusion:FSC possesses a satisfactory effect for HDUB,which can regulate menstruation,stop bleeding,promote ovulation and exert a long-term effect.