TGF-β在TAM治疗乳腺癌中的作用
摘要
TGF—β是一类具有多种生物活性的细胞因子 ,在TAM治疗乳腺癌过程中TGF—β通过调节与细胞周期相关的基因及蛋白表达使细胞停滞在Gl期 ,阻止细胞增殖 。
出处
《青海医学院学报》
CAS
2002年第4期49-51,共3页
Journal of Qinghai Medical College
参考文献14
-
1Miyazono K, Ten Dijke P, Heldin CH. TGF-β signaling by smad proteins[J]. Adr Immuno1,2000,75(1):115～157
-
2Darzynkiewiez Z, Gong J, Juan G, et al. Cytometry of cyclin proteins[J]. Cytometry, 1996,25:1～13
-
3Weinberg RA. The retinoblastoma protein and the cell cycle control [J] Cell,1995,81:323～330
-
4Zhou BB, Elledge SJ. The DNA damage response: putting checkpoints in perspective [J]. Nature, 2000, 408(6811):433～439
-
5Hoeijmakers JH. Genome maintenance mechanisms for preventing cancer[J]. Nature, 2001, 411(6835):366～374
-
6Gillett CE, Smith P, Peters G, et al. cyclin- dependent kinase inhibitor p27Kipl expression and interavtion with other cell cycle - associated proteins in mammary carcinoma[J]. J Pathol, 1999,187:200～206
-
7Reed W, Fllrenes VA, Holm R, et al. Elevated levels of p27, p21 and cyclindl correlate with positive oestrogen and progesterone receptor status in node -negative breast carcinoma patiens [J]. Virchows Arch, 1999,435:116～124
-
8Hannon GJ, Beach D. p15 is a potential effector of TGF-beta induced cell cycle arrest [J]. Nature,6 1994,371:6257～261
-
9Campbell I, Magaliocco A, Moyana T, et al. Adenovirus- mediated p16 gene transfer significantly suppresses human breast cancer growth[ J]. Cancer Gene Ther, 2000,7:1270～1278
-
10Kim M, Katayose Y, Rojanala L, et al. Induction of apoptosis in p16 mutantcell lines by adenovirous- mediated overexpression of p16 protein[J]. Cell Death Differ, 2000,7: 706～711
-
1李蓉.岩舒注射液联合化疗治疗中晚期胃癌的临床观察[J].中国社区医师（医学专业）,2006,8(16):60-60. 被引量：4
-
2曲志博,刘连新,尹大龙,陈炜,郭化鑫,杨海彦,潘尚哈,姜洪池.三氧化二砷对乳腺癌细胞凋亡及线粒体跨膜电位的影响[J].中华外科杂志,2007,45(13):883-884. 被引量：6
-
3潘启超.醛氢叶酸增强氟尿嘧啶抗癌疗效的理论与临床应用[J].国外科技,1991(9):42-46. 被引量：7
-
4邹丽娟,董志.顺铂加热后的抗癌疗效及其作用机制的研究[J].实用癌症杂志,2001,16(5):489-492. 被引量：9
-
5万华丽,张家玉.自噬在乳腺癌发生、发展中的机制和研究进展[J].海南医学,2017,28(1):119-121. 被引量：5
-
6周维国,赵丽波,谢升伟.喉癌局部免疫反应中TIL细胞亚群与TCF-β_1的作用及其相关性[J].实用肿瘤学杂志,2001,15(4):257-260.
-
7邹丽娟,王琦,邵淑娟,于丽敏,张晨,杨佩满.β-榄香烯诱发肿瘤细胞凋亡的研究[J].中国肿瘤临床,1999,26(8):616-619. 被引量：13
-
8卿三华,周锡庚,周正端,齐德林,姚明,梁立德,闻英.手术联合5－氟尿嘧啶腹腔化疗治疗结肠直肠癌的实验和临床研究[J].第一军医大学学报,1996,16(1):22-24. 被引量：8
-
9杨梅芳,黄蓉蓉,王录焕,张文娟.肺癌患者血清CEA、CT及TNF测定的临床意义[J].放射免疫学杂志,1996,9(1):9-10. 被引量：2
-
10张海青,李世业,付瑜,杨声,富廷海,秦明,吕福东,闫东杰.康莱特注射液治疗原发性肺癌的临床及病理学观察[J].中国肿瘤临床,1999,26(6):477-478. 被引量：7
