花粉提取物对带瘤小鼠胸腺T细胞数量变动的影响

INFLUENCE OF POLLEN WATER-SOLUBILITY EXTRACTION ON THE QUANTITIES OF THYMUS T LYMPHOCYTE OF TUMOR-BEARING MICE

本文报道用~3H-TdR掺入法研究花粉提取物对带瘤小鼠胸腺T细胞在有丝分裂原作用下增殖反应的影响。并用酵母多糖混合玫瑰花形成试验,观察其胸腺细胞中T、Tr和T_μ细胞数量变动的影响。实验结果表明:带瘤小鼠胸腺细胞的增殖反应均低于正常小鼠,经花粉提取物灌胃后,其胸腺细胞的增殖反应均有不同程度提高;T、Tr及T_μ细胞数均比对照组升高。说明花粉提取物具有促进免疫细胞活性的作用。

Influence of pollen water-solibility extraction on qnantities of thymus T lymphocyte marked by 3H-TdR of tumor-bearing mice was studied using Zymosan mixed rosett-forming test. The resualts indicated the percent of T lymphocyte, Tr and Tu in thymus of tumor-bearing mice were lower than that in the normal mice and were gradually veducing with the growth of tumor age. But the quantities of T cells would becincreased if the tumor-bearing mice was treated with extracts of pollen. This suggests that the pollen water-solubility extraction can enhance the activity of thymus T lymphocyte and it can be used to increase the immunity of body against different antigens.