结晶聚-L-乳酸片层粒子的制备及其对人甲胎蛋白表位肽的吸附研究

Preparation of Crystal Poly-L-Lactic Acid Lamellae and Adsorption Behavior for Human Alpha Feroprotein Epitope Peptide

用沉淀法制备了结晶聚—L—乳酸片层粒子 (片粒 ) ,考察了片粒对人甲胎蛋白CTL表位肽的吸附携载 ,吸附效率可达 70 %以上 ,是一种有前景的抗原蛋白佐剂载体 ,可望用以制备抗肝癌疫苗 。

Crystal poly-L-lactic acid(PLLA) Lamellar particles were prepared by precipitation method. The lozenge shaped particles without any surfactants show high protein adsorption efficiency for human alpha feroprotein epitope peptide up to 70%.