忍冬抗感冒颗粒质量标准研究

Studies on Quality Standard of Rendongkangganmao Keli

目的:建立忍冬抗感冒颗粒的质量标准。方法:采用TLC法对本品中山豆根、青蒿、白芷及重楼进行定性鉴别,并采用双波长薄层扫描法测定了苦参碱的含量。结果:薄层色谱斑点清晰,阴性对照无干扰;苦参碱在1.167～5.835g范围内点样量与峰面积积分值呈良好的线性关系,平均回收率为98.37%,RSD=1.07%。结论:方法可靠,结果稳定,重现性好,可作为该产品的质量控制标准。

Objectives: To establish quality standard of Rendongkangganmao Keli. Methods:Radix Sophorae Tonkinensis, Herba Artrmisiae Annuae, Radix Angelicae Dahuricae and Rhizoma Paridis were identified by thin-layer chromatography, and matrine was determined by dual wave length TLC-scanner. Results:The TLC sports developed were fairly clear, and the blank test showed no interference. A good linearity was shown at the concentration of 1.167μg to 5.835μg of matrine, the average recovery was 98.37% and the RSD was 1.07%. Conclusion:This method is reliable. The results are stable with a good repeatalility and can be used for the quality control of the preparation.