摘要
给小鼠3g/(kg.d)、6g/(kg.d)佛手醇提取液,连续15d,观察小鼠开场行为、学习记忆能力、脑单胺类神经递质(DA、5-HT、NA)含量,实验结果表明:小鼠在新环境中自发活动显著减少,学习记忆能力显著增强,脑内去甲肾上腺素、多巴胺和五羟色胺含量显著提高,金华佛手醇提取液能改善小鼠的学习记忆能力。
To investigate the effect of the ethanolic extract of Jinhua Bergamot on learning memory of mice,mice were kept on the ethanolic extract of Jinhua Bergamot,3g/kg body weight or 6g/kg body weight for 15 days.The behavior of the opening field and the learning memory were observed.The contents of DA,NA and 5-HT in brain were measured.The results showed that compared with the control group:the ethanolic extract of Jinhua Bergamot could obviously decrease spontaneity activity of mice in new environment,obviously improve the learning abilities,markedly increase the contents of DA,NA and 5-HT in brain.The conclusion is that the ethanolic extract of Jinhua Bergamot can improve the learning memory of mice.
出处
《特产研究》
2002年第4期16-18,共3页
Special Wild Economic Animal and Plant Research
基金
浙江省教委资助项目(19990501)
关键词
金华佛手醇提取液
小鼠
学习记忆
单胺类神经递质
Ethanolic extract of Jinhua Bergamot
Monoamine neurotransmitter
Learning memory