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110例癫癎患儿丙戊酸钠血药浓度监测 被引量:7

Monitoring of Blood Concentration of Sodium Valproate in 110 Cases of Ill Children with Epilepsy
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摘要 Objective: To analyse the monitoring result of sodium valproate used for patients with epilepsy. Method: Fluorescence polarization immunoassay(FPIA) was used. Result: Of the monitoring results of blood concentration in 110 cases of ill children diagnosed as epilepsy, the blood concentrations were within therapeutical range in 47.27% of patients, that were less than the range in 37.27%, that were higher than the range in 15.45%. Conclusion: The individual difference of blood concentration was large in ill children with epilepsy after taking sodium valproate, timely monitoring of blood concentration and conduct of individual administration have a important significance for controlling seizure. Objective: To analyse the monitoring result of sodium valproate used for patients with epilepsy. Method: Fluorescence polarization immunoassay(FPIA) was used. Result: Of the monitoring results of blood concentration in 110 cases of ill children diagnosed as epilepsy, the blood concentrations were within therapeutical range in 47.27% of patients, that were less than the range in 37.27%, that were higher than the range in 15.45%. Conclusion: The individual difference of blood concentration was large in ill children with epilepsy after taking sodium valproate, timely monitoring of blood concentration and conduct of individual administration have a important significance for controlling seizure.
作者 杨彤
出处 《药物流行病学杂志》 CAS 2003年第1期19-20,共2页 Chinese Journal of Pharmacoepidemiology
关键词 癫痫 丙戊酸钠 血药浓度 监测 儿童 Sodium valproate Blood concentration FPIA
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参考文献2

  • 1.血药浓度监测在小儿癫痫临床中的应用[A].梁承玮.小儿癫痫与癫痫综合征[C].北京:人民卫生出版社,1997.199.
  • 2国家药典委员会.抗癫痫药和抗惊厥药[A].国家药典委员会 主编.临床用药须知[C].北京:化学工业出版社,2001.74.

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