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AP-1与肾脏 被引量：6

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摘要 激活蛋白-1是与氧化应激相关的一类二聚体的转录调控因子。激活蛋白-1的活化在细胞增生、分化、转化、凋亡以及细胞外基质积聚中发挥重要作用。本文就其结构、活化及与肾脏固有细胞活化、实验性肾小球肾炎、糖尿病肾病、高血压肾损害和肾小管间质纤维化之间的关系作一综述。
作者 甘卫华
机构地区 南京医科大学第二附属医院儿科
出处 《国外医学（儿科学分册）》 2003年第1期1-4,共4页 Foreign Medical Sciences（Section of Pediatrics)
关键词 原癌基因蛋白质 C-JUN 肾疾病 激活蛋白1 肾疾病 治疗
分类号 R363 [医药卫生—病理学]
  • 相关文献

参考文献20

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  • 5Ruiz - Ortega M, Lorenzo O, Egido J, et al. Angiotensin Ⅱ increases MCP- 1 and activates NF- кB and AP- 1 in cultured mesangial and mononuclear cells[J]. Kidney Int, 2000,57(6): 2285- 2298.
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同被引文献112

  • 1张慧琼,易著文,何小解,何庆南,党西强,莫双红.P300在肾病综合征糖皮质激素耐药中的作用[J].临床儿科杂志,2005,23(4):205-209. 被引量：4
  • 2甘卫华,陈荣华,丁桂霞,龚晶,杨春,张文君.肾病综合征患儿肾组织中AP-1及TGF-β_1的表达与激素疗效关系的探讨[J].临床儿科杂志,2005,23(4):210-213. 被引量：9
  • 3刘志红,黎磊石.葡萄球菌肠毒素诱发的IgA肾病模型[J].中华肾脏病杂志,1989,5(1):6-10. 被引量：72
  • 4李果,肖小河,金城,李祖伦.大黄不良反应古今论[J].中华中医药杂志,2007,22(7):439-442. 被引量：12
  • 5Bray P J, Du B, Mejia VM, et al. Glucocorticoid resistance caused by reduced expression of the glucocorticoid receptor in cells from human vascular lesions. Arterioscler Thromb Vasc Biol, 1999,19 (5):1180- 1189.
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  • 7Ruiz M, Lind U, GafwAs M, et al. Characterization of two novel mutations in the glumcortimid receptor gene in patients with primary Cortisol resistanoe. Clin Endocrinol(Oxf), 2001,55 (3) : 363 - 371.
  • 8Hollenberg SM, Weinberger C, Ong ES, et al. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature, 1985,318(6047) :635 - 641.
  • 9Bamberger CM, Bamberger A, de Castro M, et al. Glucocorticoid receptor β, a potential endogenous inhibitor of glucocorticoid action in humans. J Clin Invest, 1995,95(6) :2435 - 2441.
  • 10Shahidi H, Vottero A, Stratakis CA, et al. Imbalanced expression of the glucocorticoid receptor imforms in cultured lymphocytes from a patient with systemic glucocorticoid resistance and chronic lymphocytic leukemia. Biochem Biophys Res Commum, 1999, 254(3) :559 - 565.

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国外医学（儿科学分册）
2003年 第1期

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