肝细胞癌伴门静脉癌栓的介入治疗进展
摘要
肝细胞癌伴门静脉癌栓的临床发生率较高,癌栓可通过门静脉血流向肝内外播散,导致肿瘤术后复发与转移,临床预后极差。既往缺乏理想的介入治疗方法。近年来,随着分子生物学与影像医学的不断发展与完善,有关门静脉癌栓的发生发展机制被进一步阐明,其临床介入治疗的研究亦取得了可喜的突破。
参考文献19
-
1Shuto T,Hirohashi K,Kubo S,et al.Efficacy of major hepatic resection for large hepatocellular carcinoma.Hepatogastroenterology,1999,46(25):413-416
-
2Chan MK,Kwok PC,Chan SC,et al.invasion of the portal ein:detection using lipiodol computed tomography.Apropos of 2 cases.Vasc Interv Radiol,1999,10(5):641-647
-
3Minagawa M,Makuuchi M,Takayama T,et al.Selection criteria for hepatectomy in patients with hepatocellular carcinoma and portal vein tumor thrombus.Ann Surg,2001,233(3):397-404
-
4Koga H,Sakisaka S,Ohishi M,et al.Expression of cyclooxygenase-2 in human hepatocellular carcinoma:relevance to tumor dedifferentiation.Hepatology,1999,29(3):688-696
-
5Chen WS,Lchikura T,Mochizuki H,et al.Tumor invasiveness and liver metastasis of colon caner cells correlated with cyclooxyenase-2(cox-2)expression and inhibited by a cox-2-selective intibitor,etodolac.Int J Cancer,2001,91(6);896-899
-
6Pavco PA,Bouhana KS,Gallegos AM,et al.Antitumor and antimetastasic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptor.Clin Cancer Res,2000,6(5):2094-2103
-
7Hofmann UB,Westphal JR,Van Kraats AA,et al.Expression of integrin alpha(v) beta(3) correlates with activation of man brare-type matrix metalloproteinase-1(MT-1MMP) and matrix metalloproteinase-2(MMP-2) in human melanoma cells in vitro and in vivo.Int J Cancer,2000,87(1):12-19
-
8Llovert JM,Bustamante J,Castells A,et al.Natural history of untreated nonsurgical hepatocellular carcinoma:rationale for the design and evaluation of therapeutic trials.Hepatology,1999,29(1):62-67
-
9Okada S,Okazaki N,Nose H,et al Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy.Hepatology,1992,16(1):112-117
-
10Chung JW,Park JH,Han JK,et al.Hepatocellular carcinoma and portal vein invasion:results of treatment with transcatheter oily chemoembolization.AJR,1995,165(2):315-321
-
1姜泊,周殿元,张亚历.大肠癌基因诊断的研究现状[J].现代消化病及内镜杂志,1996,1(1):51-55.
-
2周立新,郭剑民,张云利,杜义安.肝细胞癌合并门静脉癌栓的外科治疗[J].肿瘤研究与临床,2003,15(3):183-184.
-
3简雪平,文辉才,韩超,廖怀伟.恶性黑色素瘤的基因治疗新进展[J].南昌大学学报(医学版),2013,53(1):90-92. 被引量:6
-
4黄杨卿,程树群,吴孟超.化疗对肝癌门静脉癌栓治疗的现状和进展[J].肝胆外科杂志,2003,11(4):311-313. 被引量:2
-
5黄洁.癌基因、抑癌基因与卵巢癌基因治疗[J].国外医学(妇产科学分册),1998,25(4):205-209. 被引量:1
-
6周建光,杨梅.前列腺癌标志物研究的新进展[J].临床和实验医学杂志,2010,9(15):1182-1183.
-
7孙应实,张晓鹏.直肠癌全直肠系膜切除术的术前MRI评价[J].当代医学,2010,16(8):77-82. 被引量:5
-
8刘宝华.腹腔镜结直肠癌手术的并发症及对策[J].肿瘤预防与治疗,2008,21(3):242-245. 被引量:13
-
9王存川,胡右主,徐以浩.腹腔镜结直肠癌手术的选择与应用[J].大肠肛门病外科杂志,2003,9(1):3-4. 被引量:20
-
10徐兴华,王祎波,徐硕.组织间植入放射性^(125)I粒子治疗直肠癌[J].中国现代普通外科进展,2012,15(6):425-425. 被引量:2