口腔粘膜游离移植再造尿道

Autologous buccal mucosal graft for urethral reconstruction

目的 探讨采用口腔粘膜游离移植 ,对局部缺乏组织的尿道下裂行尿道再造的方法。方法 1998～ 2 0 0 1年对 2 5例患者应用口腔粘膜游离移植再造阴茎段尿道 ,半年后吻合瘘口。结果 1例一期术后并发感染 ,愈后无尿道狭窄 ,所有病例二期吻合瘘口后 ,再造尿道通畅。结论 口腔粘膜丰富的网状毛细血管网、韧厚的上皮层和相对较薄的皮下板层结构是移植成功的关键。以口腔粘膜游离移植行尿道再造是一种可行的方法。

ObjectiveTo search for a new method for urethra reconstruction using autologous buccal mucosal graft while lacking of local skin. Methods Since 1998, a total of 25 patients with complex hypospadias have been treated using buccal mucosal grafts for urethral reconstruction. The reconstructed urethra was anastomosed with the meatus half year later. Results All the reconstructed urethra survived without contracture or stricture except one infection, which healed with no adverse consequence. ConclusionThe key points for operation success is rich capillary network, thick epidermis and thin lamina propria of the buccal mucosa. Buccal mucosa is an excellent tissue for urethral reconstruction.;