摘要
为建立三黄痔疮膏中大黄素的质控标准。采用HPLC的方法进行含量测定 ,以乙醇为溶剂提取有效成分 ,去除基质。以甲醇 0 1%磷酸 (9∶1)为流动相 ,C18柱测定了大黄素的含量。结果测得三黄痔疮膏中大黄素含量为 0 0 6 6 3mg/g ,平均加样回收率 96 5 %。提示该法有效去除了栓剂基质对含量测定的影响 ,方法简便、准确、灵敏。
To establish quality control standards for emodin in 'San Huang Zhi Chuang Ointment',HPLC method was applied to assay the content of emodin in the ointment.Results:The content of emodin in the ointment was 0 0663mg/g and its average recovery rate was 96 5%.It is proved that HPLC method is a simple,accurate and exact method.
出处
《上海中医药杂志》
北大核心
2003年第1期49-50,共2页
Shanghai Journal of Traditional Chinese Medicine
