紫苏油及大豆肽合剂对大鼠血脂的调节作用

Effects of mixture of Prilla frutescens(L.) Britt.oil and soybean peptide on blood lipid in rats

目的 :研究大豆肽和紫苏油相结合的产品降脂肽对高血脂模型动物血脂的影响 ,以及停服上述降脂合剂 1周后维持降脂的时间。方法 :将 4 0只SD大鼠分为 4组。用含 88%紫苏油和 12 %大豆肽制备的降脂合剂给予高脂饮食饲养的大鼠连续灌胃 4 0d后 ,取血测定血清胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白 (HDL)。停止用药 1周后 ,再测血脂 1次。结果 :实验组血清TC及TG浓度明显低于高血脂模型对照组 (P 0 .0 1) ,而HDL浓度则明显高于高血脂模型对照组 (P <0 .0 5 )。停止降脂制剂灌胃 1周后 ,仍可使血清TG维持在较低水平。结论 :由食。

Objective:The effect of mixture of Prilla frutescens(L.) Britt. oil and soybean peptide on blood lipid in hyperlipoidemia model rats and the keeping time of low level of blood lipid one week after non taking the reducing blood lipid mixture were studied. Methods:40 SD rats were divided into 4 groups. The reducing blood lipid mixture contained 88% Prilla frutescens(L.) Britt. oil and 12% soybean peptide was irrigated to stomach lasting 40 days in high blood lipid model rats those were fed with high lipid food. The Serum cholesterol (TC) , triglyceride (TG) and high density lipoprotein (HDL) were tested 40 days after taking the reducing blood lipid mixture and one week after non taking in all experimental animals. Results:The level of serum CT and TG of experimental group were significantly lower than those in high blood lipid model control group(P< 0.01 ), but serum high density lipoprotein was significantly higher than that in high blood lipid model control group(P< 0.05 ). One week after stopping taking of reducing blood lipid mixture, the serum triglyceride was maintained yet at a lower level. Conclusion:The reducing blood lipid mixture extracted from nature plants that are used in diet and medicine indeed can decrease blood lipid concentration notably and can prevent hyperlipidemia.