摘要
目的 :提出一种简单实用的色谱指纹图谱相似度计算方法。方法 :将色谱指纹图谱的重叠率和共有峰的峰强度结合计算相似度。结果 :将该算法应用于两篇文献中的样品指纹图谱 ,结果与实际完全一致。结论 :用本文提出的方法计算相似度能敏感反映谱图间的差异 ,计算简单 。
Objective: To provide an easy and feasible algorithm of the similarity between chromatographic fingerprints of herbs. Methods: To calculate similarity by combining the chromatographic overlap rate with relative area or height of mutual peaks of chromatographic fingerprints. Results: The algorithm was applied to the chromatographic fingerprints of samples in two references and the result is consistent with the fact. Conclusion: The calculated similarity with the proposed method can be sensitive to indicate the difference between fingerprints of herbs and the provided algorithm is simple and easy to be used.
出处
《中成药》
CAS
CSCD
北大核心
2003年第1期4-8,共5页
Chinese Traditional Patent Medicine