轮状病毒性肠炎与继发性乳糖不耐受关系分析

TO INVESTIGATE THE RELATIONSHIP BETWEEN ROTAVIRUS ENTERITIS AND SECONDARY LACTOSE INTOLERANCE

目的 :探讨轮状病毒性肠炎与继发性乳糖不耐受的关系。方法 :对 2 0 0例轮状病毒性肠炎患儿用醋酸铅加氢氧化氨法检测粪乳糖 ,PH值 ,粪乳糖≥ ++、PH <5 .5 ,为乳糖不耐受症、将其分治疗Ⅰ组及治疗Ⅱ组 ,粪乳糖阴性为对照组。结果 :2 0 0例轮状病毒性肠炎中粪乳糖≥ ++,PH <5 .5 ,138例 ,其中年龄≤ 6月 32例 ,≤ 1岁 6 8例 ,≤ 2岁 36例 ,≤ 3岁 2例。治疗I组和治疗Ⅱ组临床症状较对照组重 ,差异明显 (P <0 .0 1) ,治疗Ⅰ组与对照组疗效无明显差异 (P >0 .0 5 ) ,治疗Ⅱ组与对照组疗效比较差异明显 (P <0 .0 1)。结论 :轮状病毒性肠炎容易导致继发乳糖不耐受症 ,且年龄越小 ,越容易发生 ,去乳糖饮食治疗轮状病毒性肠炎继发乳糖不耐受症疗效显著 ,对轮状病毒性肠炎患儿应检测粪乳糖及PH ,及早发现继发性乳糖不耐受症。

Objective:To investigate the relationship between rotavirus enteritis and secondary lactose intolerance. Methods:Examine feces lactose,PH in two hundreds patients with rotavirus enteritis with the way of lead acetate with aqueon ammonia, feces lactose ≥++ , PH<5.5 are diagnosed secondary lactose intolerance.Divided group Ⅰ and group Ⅱ.Patients of feces lactose<++ , PH<5.5 is called the control group. Results:138 cases Of 200 cases are diagnosed secondary lactose intolerance,age≤6-month 32cases,≤ 1-year 68 cases,≤2-year 36 cases,≤3-year 2 case. There was a significant in chinical symptons between group or group Ⅱ and the control group ( P <0.01).There was no difference in therapeutic effect of disease between group and the control group( P > 0.05 ).There was a significant in therapeutic effect of disease between the group Ⅱ and the control group( P < 0.01 ). Conclusions:It was noticed that there was a higher incidence of secondary lactose intolerance in the children with rotavirus enteritis.The younger the infants were,the higher the incidence of secondary lactose intolerance would be. Non-lactose diet is a effective therapy, it is suggested that every child with rotavirus enteritis should be screened for secondary lactose and should be treated with non-lactose diet,once he or she is identified to have secondary lactose.