摘要
目的:观察快中子、光子及快中子加光子混合射线照射小鼠胸腔后心肌的病理改变。方法:168只小鼠被随机分为快中子组、光子组、混合线组(快中子加光子)。分别照射等效快中子、光子及快中子加光子混合射线,每个剂量点均在照射后第3,14和28天分别取6只小鼠断颈处死,开胸取出心脏后用10%福尔马林固定,常规切片HE染色后在光镜下观察。结果:在照射后第3,14和28天,3组小鼠心肌的病理改变基本一致,无显著差异。结论:快中子加光子混合射线照射小鼠胸腔后,不会加重心肌放射损伤,对临床应用混合射线治疗胸部肿瘤有一定的指导意义。
Objective:To observe the heart p athologi cal changes after thoracic irradiation with different rays.Methods:The thorax of168mice were irradiated with equal effective fast neutron,photon and mixe d beamed,respectively.Results:There were no difference found in the pathologi cal changes of heart after the three kinds of beam irradiation.Conclusion:The radia-tion reactions of the mice heart seem not to be deteriorated after thorac ic irradiation with fast neutron,photon or mixed beams.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2003年第1期53-54,57,共3页
Chinese Journal of Clinical Oncology
基金
国家攀登计划B项目基金
