复发性腹膜后肉瘤的治疗及其预后(附36例报告)

Treatment and prognosis of 36 patients with recurrent retroperitoneal soft tissue sarcomas

目的 探讨复发性腹膜后肉瘤的治疗及其预后。方法 回顾性分析 1988～ 1999年收治的 36例 ,复发性腹膜后肉瘤的临床资料。结果 除 7例仍在 2年治疗中 ,余 2 9例中 2 7例生存 3年以上 ,12例生存 5年以上 ,5年生存率为 4 1.4 %。手术次数和有无合并脏器切除与生存无明显关系。结论 外科手术切除肿瘤是提高复发性肉瘤生存率最重要的手段 ,对多次复发的肿瘤不应放弃手术机会 ,放疗和化疗对复发性肉瘤可起一定的控制作用。

Objective To investigate the treatment and the prognosis of patients of patients with recurrent retroperitonesl soft tissue sarcomas.Methods The clinical data of 36 patients,treated for recurrent retropertoneal.Soft tissue sarcomas from 1988 to 1999 were analyzed retrospectively. Results Seven cases were followed less than 2 years,27 cases survived more than 3 years,12 cases survived five and more than five years.The five years survived rate was 41.4%.The number of operation and maltiple organ resection have no relationship with survival rate. Conclusion Surgery is effective in improving the survival rate of patients with recurrent retroperitoned soft tissue sarcomas,including those with repeatedly recurrent sarcoma.Adjuvant radiotherapy and chemotherapy might improve the local control of relapsed sarcomas to some extent.