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生脉散合炙甘草汤加减液对感染柯萨奇B_3病毒培养大鼠心肌细胞的保护作用 被引量:6

PROTECTIVE EFFECT OF CHINESE MEDICINE COMPOUND ON CULTURED RAT'S MYOCAROIAL CELLS INFECTED WITH COXSACKIE VIRUSB_3
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摘要 目的 :探讨生脉散合炙甘草汤加减液对病毒性心肌炎的保护作用。方法 :实验取新生SD大鼠心室肌制备搏动心肌细胞 ,培养 48h后添加 10 3 TCID50 的柯萨奇B3 病毒作为实验性病毒性心肌炎模型 ,观察中药复方对心肌细胞的保护作用。结果 :生脉散合炙甘草汤加减液明显提高细胞搏动百分比 ;明显增加细胞内糖原颗粒数目 ,增强琥珀酸脱氢酶活性 ,降低乳酸脱氢酶活性。结论 :生脉散合炙甘草汤加减液对感染柯萨奇B3 Objective:To study the protective effect of pulse-activating powder combined with the roast Glycyrrhiza decoction adjusted juice on the cultured rat's myocardial cells infected with coxsackie virus B 3.Methods:The beating myocardial cells obtained from the ventricular myocardium of newborn Sparaque-Dawley rats,were incubated for 48 hours and inoculated with 10 3TCID50 of B 3 virus as experimental model of viral myocarditis(VMC). Results:PGP increased percent of cell beating;increased glucogen granule in myocardial cells,enhanced the activity of SDH,reduced the activity of LDH.Conclusion:PGP have protective effect on SD rat's myocardial cells infected with CVB 3
机构地区 延边大学医学院
出处 《中国中医药科技》 CAS 2002年第5期272-273,256,共2页 Chinese Journal of Traditional Medical Science and Technology
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  • 1A. K. Foulis,M. A. Farquharson,S. O. Cameron,M. McGill,H. Sch?nke,R. Kandolf. A search for the presence of the enteroviral capsid protein VP1 in pancreases of patients with Type 1 (insulin-dependent) diabetes and pancreases and hearts of infants who died of coxsackieviral myocarditis[J] 1990,Diabetologia(5):290~298

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