孕妇外周血中游离胎儿DNA的生物学及其在产前诊断中的应用
摘要
孕妇外周血中游离胎儿DNA的存在 ,为非侵入性产前基因诊断开辟了崭新途径 ;检测手段的简便、高效及胎儿DNA的稳定性使我们在对性连锁遗传病及单基因遗传病进行产前诊断方面又有了新的进展。同时 ,血中游离胎儿DNA的浓度改变也与某些妊娠病理息息相关。这些均为今后的产前诊断及研究母胎间关系提供了更多思路。
出处
《国外医学(妇幼保健分册)》
2002年第5期197-199,共3页
Foreign Medical Sciences (Section of Maternal and Child Health)
参考文献20
-
1Walknowska J, Conte FA, Grumbach MM. Practical and theoretical implication of fetal/maternal lymphocyte transfer[J]. Lancet, 1969,1:1119-1122.
-
2Lo YMD, Corbetta N, Chamberiain PF, et al. Presence of fetal DNA in maternal plasma and serum[J]. Lancet, 1997, 350:485-487.
-
3Smid M, Lagons F, Papasergo N,et al. The timing of fetal DNA retrieved in the maternal blood and prenatal gender diagnosis by PCR[J]. The AJ Human Genet, 1999, 59(4):A142.
-
4Perit B, Samura O, Sekizawa A, et al. Detection of male and female DNA in maternal plasma by multiplex fluorescent PCR amplification of short tandem repeats(STRs) [J]. A J Human Genet,1999,65(4):A77.
-
5Lo YMD. Fetal DNA in maternal plasma: biology and diagnostic applications[J]. Clinical Chemistry, 2000, 46:1903-1906.
-
6Binchi DW,Zvickwolf GK, Weil GJ,et al. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum[J]. Proc Natl Acad Sci U S A ,1996, 93:705-708.
-
7Lo YMD, Zhang J, Leung TN,et al. Rapid clearance of fetal DNA from maternal plasma[J].Am J Hum Genet,1999,64: 218-224.
-
8Botezatu I, Serdyuk O ,Potapova G, et al. A new approach for detecting specific genomic DNA sequences from cells dying in an organism[J]. Clin Chem,2000,46:1078-1084.
-
9Zhang J, Tong KL, Li PK, et al. Presence of donor and recipient-derived DNA in cell-free urine samples of renal transplantation recipients: urinary DNA chimerism[J]. Clin Chem, 1999, 45: 1741-1746.
-
10Zhong XY,Hahn D, Troeger C, et al. Cell-free DNA in urine: a marker for kidney graft rejection, but not for prenatal diagnosis[J]? Ann N Y Acad Sci, 2001,945: 250-257.
-
1侯慧利.心理护理对妊娠剧吐的影响[J].适宜诊疗技术,2002,20(6):35-36.
-
2杨丽娟,张亚维,郭宏娟.子宫腺肌症合并妊娠临床病例分析[J].中华当代医学,2004,2(9):74-74.
-
3钱虹,李丽娟,殷萍萍.502例早产的发病因素与防治[J].黑龙江医学,1998,0(10):10-11.
-
4曹建初,曾宪筠,姜淑芬.输卵管妊娠病理误诊分析[J].贵阳医学院学报,1996,21(2):139-139.
-
5任平,严新民,杨燕,张丽萍,华映昆,张云霞,马艳萍.肿瘤坏死因子α与流产的关系[J].云南医药,1997,18(5):333-334. 被引量:4
-
6任华,王俏霞,郭凌岑.细菌性阴道病与流产关系的探讨[J].中国优生与遗传杂志,2003,11(6):103-103. 被引量:8
-
7陈常霞.临产妇的心理状态调查与护理[J].中国煤炭工业医学杂志,2010,13(8):1226-1227. 被引量:1
-
8邢素娟.超声下不孕症患者子宫内膜容受性的研究[J].世界最新医学信息文摘,2015,0(87):102-103. 被引量:1
-
9邱丽蓉.宫外孕52例临床分析[J].亚太传统医药,2010,6(10):114-115.
-
10戴青里,杨慧东,张纯.超声诊断羊水过多与胎儿畸形的关系[J].中国医疗前沿,2011,6(17):60-61. 被引量:3