三个新甾体皂甙元的结构鉴定

Structural Elucidation of Three New Steroid Sapogenins

从中药蒺藜TribulusterrestrisL .(Zygophyllaceae)中分离纯化得到 5个甾体皂甙元 ,经IR ,2D NMR和MS等波谱技术分别鉴定为 :海可皂甙元 (1) ,2 5 (R) 螺甾烷 4 烯 3,12 酮 (2 ) ,2 5 (R) 螺甾烷 3,5 二烯 12 酮(3) ,2 5 (R) 螺甾烷 4 烯 2 β ,3α 二羟基 12 酮 (4)和 2 5 (R) 螺甾烷 2 4 β 羟基 4 烯 3,12 酮 (5 ) ,其中化合物 3～

Three new steroid sapogenins, 25(R)-spirostane-3,5-diene-12-one (3), 25(R)-spirostane-2beta, 3a-diol-4-ene-12-one (4), 25 ( R)-spirostane-24beta-ol-4-ene-3,12-dione (5), together with two known compounds, hecogenin (1), and 25(R)-spirostane-4-ene-3,12-dione (2), were isolated from Tribulus terrestris L. Their structures were elucidated by the spectral analyses.