1Miyanohara A,Yee JK,Bouie K, et al.Efficient in vovo transduction of the n eonatal mouse liver with pseudotyped retrovival vectors [J].Gene Ther 1995 Mar;2(2):138
2Takahashi-H, Fujimoto-J,Hanada-S et al.Acute hepatitis in rats expre ssing humen hepatitis B virus transgenes[J].Proc-Natl-Acad-Sci-U-S-A.1995 Feb 28;92 (5):1470
3Pourcel C,Tiollais P,Farea H.Transcription of the S gene in transgen ic mic e is associated with hypomethylation at specific sites and with Dnase I sensi tivity [J].J virol 1990Feb;64(2): 931
4Akmal M,EL-Ghor A,Burk RD.Dnase I hypersentitive site maps to the HB Venhancer[J]. Virology1989 Oct;172(2):478
5Aragona E,Burk RD,Ott M, et al .Cell type-specific mechanisms regula te hep atitis B virus transgene expression in liver and other organs[J].J Pathol 19 96 Dec;180(4):441
6Farea H,Salmon AM,Hadchouel M ,et al.Hepatitis B surface antigen gen e exp ression is regulated by sex and glucocorticoids in transgenic mice[J].Pro c Natl Acad Sci USA,1987; 84:1187
7Reifenberg K,Wilts H,Lohler J , et al.The hepatitis B virus X protei n tran sactivates viral core gene expression in vivo[J].J Virol 1999 Dec;73(12): 1039 9
8Hu JF,Cheng Z,Chisari FV;,et al.Repression of hepatitis B virus (HBV ) tran sgene and HBV-induced liver injury by low protein diet [J]. Oncogene 1997 Dec 4;15(23):2795
9Huang SN,Chisari FV.Strong,sustained hepatocellular proliferation pr ecedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mic e[J]. Hepatology,1995,21 (3):620
10Terradillos O,Billet O,Renard CA,et al.The hepatitis B virus X gene potent iates c-myc induced liver oncogenesis in transgenic mice[J].Oncohene 199 7 Jan 30 ;14(4):395
