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STZ引起的短期Ⅰ型糖尿病对大鼠背根神经节CGRP mRNA水平的影响 被引量:1

The effects of short-term type Ⅰ diabetes on CGRP mRNA in DRG of STZ-induced diabetes rats
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出处 《中国药理学通报》 CAS CSCD 北大核心 2002年第5期596-597,共2页 Chinese Pharmacological Bulletin
基金 国家自然科学基金资助项目 No 3 9970 3 49
关键词 糖尿病 背根神经节 降钙素基因相关肽mRNA 反向聚合酶链反应 动物实验 diabetes dorsal root ganglion (DRG) calcitonin gene related peptides (CGRP) mRNA RT PCR
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参考文献8

  • 1Sheykhzade M, Dalsgaard GT, Johansen T et al. The effect of long-term streptozotocin-induced diabetes on contractile relaxation responses of coronary arteries: Selective attenuation of CGRP-induced relaxations. Br J Pharmacol, 2000;129(6):1212~8
  • 2Rittenhouse PA, Marchand JE, Chen J et al. Streptozotocin-induced diabetes is associated with altered expression of peptide-encoding mRNAs in rat sensory neurons. Peptides, 1996; 17(6), 1017~22
  • 3Bell D, McDermott BJ. Calcitonin gene-related peptide in the cardiovascular system: Characterization of receptor populations and their (patho) physiological signicance. Pharmacol Rev, 1996; 48(2), 253~88
  • 4王宪,孙威,邢立愚,宫海滨,郭静萱.糖尿病大鼠肠系膜动脉降钙素基因相关肽释放减少以及一氧化氮的作用[J].生理学报,1998,50(2):206-212. 被引量:8
  • 5Troger J, Humpel C, Kremser B et al. The effect of streptozotocin-induced diabetes mellitus on substance P and calcitonin gene-related peptide expression in the rat trigeminal ganglion. Brain Res, 1999; 842(1), 84~91
  • 6Unger JW, Klitzsch Y, Pera S et al. Nerve growth factor (NGF) and diabetic neuropathy in the rat: Morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord. Exp Neurol, 1998; 153(1):23~34
  • 7Tomlinson DR, Fernyhough P, Diemel LT. Role of neurotrophins in diabetic neuropathy and treatment with nerve growth factors. Diabetes, 1997; 46 (Suppl 2):S 43~9
  • 8Mulder Y, Zhang H, Danielsen N et al. Islet amyloid polypeptide and calcitonin gene-related peptide expression are down-regulated in dorsal root ganglia upon sciatic nerve transection. Brain Res Mol, 1997; 47(1~2):322~30

二级参考文献7

  • 1Tang Y,Shock,1997年,7卷,225页
  • 2王宪,Br J Pharmacol,1996年,118卷,2164页
  • 3Rittenhouse P A,Peptides,1996年,17卷,1017页
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共引文献7

同被引文献8

  • 1Sheykhzade M, Dalsgaard GT, Johansen T, et al. The effect of long-term streptozotocin-induced diabetes on contractile and relaxation responses of coronary arteries: selective attenuation of CGRP-induced relaxations[J]. Br J Pharmacol, 2000,129(6) : 1212 -1218.
  • 2Nemeth J, Szilvassy Z, Than M, et al. Decreased sensory neuropeptide release from trachea of rats with streptozotocin-induced[J]. Eur J Pharmacol, 1999, 369(2) : 221 -224.
  • 3Zochodne DW, Verge VM, Cheng C, et al. Does diabetes target ganglion neurons? Progressive sensory neuron involvement in long-term experimental diabetes[J]. Brain,2001,124(pt 11 ) : 2319 -2334.
  • 4Miyamoto Y, Yomeda M, Morikawa A, et al. Gastric neuropeptides and gastric motor abnormality in sU'eptozotocin-induced diabetic rats: observation for four weeks after sU'eptozotocln [ J]. Dig Dis Sci, 2001,46(8) : 1596 - 1603.
  • 5Akkina SK, Patterson CL, Wright DE. GNDF rescues nonpeptidergic unmydinated primary afferents in streptozotocin-treated diabetic mice[J]. Experimental Neurology, 2001,167(1 ) : 173 - 182.
  • 6Salem N, Dunbar JC. The.insulin-mediated vascular and blood pressure responses are suppressed in CGRP-deficient normal and diabetic rats[J]. Diabetes Metabolism Research & Review, 2002, 18(3) : 238 -244.
  • 7Unger JW, Klitzseh T, Pera S, et al. Nerve growth factor (NGF)and diabetic neuropathy in the rat: morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord[J]. Experimental Neurology, 1998,153 ( 1 ) :23 - 34.
  • 8王真,郭静萱,王宪,赵一鸣,侯凌飞,曾辉.降钙素基因相关肽与冠状动脉病变关系的探讨[J].中华内科杂志,2001,40(11):750-752. 被引量:4

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