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男性不育症相关基因的研究进展 被引量:15

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摘要 根据WHO统计:育龄夫妇中约10%不能生育,其中与男性因素有关的约占50%[1].男性不育病人中绝大多数为不明原因性不育症,一般将其分为特发性无精子症、少精子症、弱精子症和畸形精子症.
作者 曹文雷
出处 《中国男科学杂志》 CAS CSCD 2002年第5期398-401,共4页 Chinese Journal of Andrology
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  • 1Pryor J C,Kent-First M,Muallem M,et al.Microdeletions in the Y chromosome of infertile men.New Eng J Med 1997;336:534-539
  • 2Kostiner,DR,Turek,PJ Reijo,RA.Male infertility:analysis of the makers and genes on the human Y chromosome.Hum Reprod 1998;13,3032-3038
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  • 7Vogt PH,Edelmann A,Kirsch S,et al.Human Y chromosome azoospermia function(AZF) mapped to different subregions in Yq11.Hum Mol Genet 1996;5(7):933-943
  • 8Kent-First M,Muallem A,Shultz J,et al.Defining regions of the Y chromosome responsible for male infertility and identification of a fourth AZF region (AZFd) by Y chromosome microdeletion detection.Mol Reprod Dev 1999;53:27-41
  • 9Saut N,Terriou P,Navarro A,et al.The human Y chromosome genes BPY2,CDY1 and DAZ are not essential for sustained fertility.Mol Hum Reprod 2000 Sep;6(9):789-793
  • 10Kleiman SE,Lagziel A,Yogev L,et al.Expression of CDY1 may identify complete spermatogenesis.Fertil Steril 2001 Jan;75(1):166-173

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