药物对进驻高原青年睡眠剥夺及运动时心功能指数的影响

The effect of medicine on sleep deprivation and heart function indicator of youth who immigrated to high altitude regions

目的 :探讨红景天与乙酰唑胺对进驻高原青年睡眠剥夺及运动时心功能指数的影响。方法 :将进驻海拔 370 0m一个月的 2 4名健康青年随机分为 3组 ,每组 8人。让受试者做坐位踏车运动。计算每位受试者的心功能指数。第二次实验为2 4h睡眠剥夺后 ;第三次实验为 3组受试者分别口服三普红景天、乙酰唑胺和安慰剂 2 0d后 ;第四次实验为服药后 2 4h睡眠剥夺后 ,实验方法与第一次相同。结果 :红景天组和乙酰唑胺组心功能指数服药后与服药后睡眠剥夺后较服药前、睡眠剥夺后及对照组明显增高 ,差异显著 (P <0 0 5 ) ,但乙酰唑胺对人体有不良反应。结论 :三普红景天与乙酰唑胺均能改善高原移居青年的心功能及提高做功效率 。

Purpose:To study how Rhulida and Acetazolamide affect sleep deprivation and heart function indicator during moving of youths who immigrated to highland.Method:Separate 24 healthy youths who have lived at the altitude of 3700m for l month into 3 groups randomly with each group has 8 persons.Let the objects do tiead cycle on seated movement and calculate the heart function indicator of each person.Do the second test after 24 hours.sleep deprivation.Do the third test when the 3 groups have taken Rhulida,Acetazolamide and stayed there separately for 20 days.Do the fourth test after taking the medicine and 24 hours' sleep deprivation as the first one.Result:Compare the heart function indicators of the group used Rhulida,the group used Actazolamide and of sleep deprivation after taking medicine with the persons of sleep deprivation before taking medicine and of the control group,the former objects increased obviously.The difference is apparent (P<0 05),but Acetazolamide has bad effect on human body.Conelusion:Rhulida and Acetazolamide can improve the heart function and increase the acting efficiency of youths who immigrated to highland but Rhulida is better than Acetazolamid.