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巯基乙酸乙酯的酯化合成工艺改进 被引量：3

Improved process of ethyl-2-mercoptocetate esteificatim synthesis
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摘要 以巯基乙酸为原料 ,用硫酸提供酸性条件 ,采用精馏脱水酯化工艺 ,提高了酯化收率 5 %～ 8% ,反应时间缩短了 10h。 Mercaptearetic acid as raw material and sulphur as acid condition, the article discusses a systhesis process of rectification deprivation esteificatim, which can not noly get a higher conversion of 5%-8% but also shorten the reaction time by 10 hours.
作者 陈裕清
机构地区 泰州职业技术学院
出处 《天津化工》 CAS 2003年第1期41-42,共2页 Tianjin Chemical Industry
关键词 巯基乙酸乙酯 酯化 合成 工艺 改进 蒸馏 rectification deprivation esteificatim ethy1-2-mercoptocetate synthesis
分类号 TQ225.241 [化学工程—有机化工]
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  • 1方登志,李彪,胡同美,王传琦.合成巯基乙酸-2-乙基己酯的新工艺[J].塑料助剂,2006(5):25-28. 被引量：2
  • 2DengY, Zhou X, Desmoulin S. et al. Synthesis and biologi- cal activity of a novel series of 6-substituted Thieno [ 2,3- d] pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry [ J ]. J Med Chem, 2009,52 ( 9 ) : 2940- 2951.
  • 3Dai Y,Guo Y,Frey R R. et al. Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase in- hibitors[ J] J Med Chem,2005 ,48(19 ) :6066-6083.
  • 4Peng J,Lin W,Jiang D,et al. Preparation of a 7-aryhhieno [ 3,2-d ] pyrimidin-4-amine Library [ J ]. J Comb Chera, 2007,9(3) :431-436.
  • 5Massimo P, Pietro B, Marco T. Synthesis of 3H-thieno[ 3, 2-c]-1,2-dithiole-3-thione and its reaction with n-butyl- amine [ J ]. J Heterocycl Chem, 1995,32 (3) :847-850.
  • 6Crespo M L, Pages L, Vega A, et al. Design, synthesis, and biological activities of new thieno [ 3,2-d ] pyrimi- dines as selective type 4 phosphodiesterase inhibitors [ J ]. J Med Chem,1998,41( 21) :4021-4035.
  • 7MUNCHHOF M J,BEEBE J S,CASAVANT J M,et al. Design and SAR of thienopyrimidine and thienopyridine inhibitors of VEGFR-2 kinase activity [ J ]. Bio. Med. Chem. Lett. ,2004,14( 1 ) :21-24.
  • 8DAI Yu-jia, GUO Yan, FREY R R, et al. Thienopyrimi- dine ureas as novel and potent muhitargeted receptor tyrosine kinase inhibitors [ J ]. J. Med. Chem. , 2005,48 (19) :6 066-6 083.
  • 9PENG Jin-song, LIN Wen-qing, JIANG Da-hong, et al. Preparation of a 7-arylthieno [ 3,2-d ] pyrimidin4-amine library [ J ]. J. Comb. Chem. , 2007,9 ( 3 ) : 431-436.
  • 10MASSIMO P,PIETRO B,MARCO T. Synthesis of 3H- thieno [ 3,2-c ] -1,2-dithiole-3-thione and its reaction with n-butylamine [ J ]. J. Heterocycl. Chem. , 1995,32 (3) :847-850.

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天津化工
2003年 第1期

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