摘要
采用Laurell’s火箭电泳法对急性心梗(AMI)患者的蛋白 C PC:Ag),总蛋白 S(TPS)和游离蛋白S(FPS)进行了检测。AMI患者入院当天及第14天的PC系统指标无明显改变,但急性期死亡患者的PC:Ag及FPS明显低于对照组(P<0.05,P<0.02);再发梗塞患者的PC:Ag和FPS亦明显低于正常对照组(p<0.05,p<0.02),TPS明显高于对照组(P<0.05)。AMI患者PC:Ag与ATⅢ:Ag呈直线负相关。
The plasma concentration of protein C (PC: Ag), total protein S (TPS) and free protein S (FPS) were determined in 17 cases of AMI with Laurell's rocked immunoelectrophoresis. It was found that the levels of PC: Ag, TPS and FPS were normal immediately of MI, but in patients who died within 10 days after onset on admission levels of PC: Ag and FPS were much lower than in the control group (P<0. 05 and P<0. 02, respectively). In comparison with healthy subjects, the levels of PC: Ag and FPS in patients with reinfarction were significantly decreased (P<0. 05 and P<0. 02, respectively), TPS values were significantly elevated (P<0. 05). PC: Ag correlated negatively with ATⅢ: Ag (r=-0. 556, P<0. 05).
关键词
心肌梗塞
蛋白
acute myocardial infarction
protein C
protein S
