感染性脱鞘性多发神经病患者膈神经根传导时间的研究

Phrenic radix conduction time in inflammatory demyelinating polyneuropathy patients

目的 初步探讨膈神经根传导时间在感染性脱鞘性多发神经病 (IDP)患者的应用及特点。方法 以表面电极在肋间隙处记录 2 0例感染性脱鞘性多发神经病患者的经项磁刺激膈神经根和经颈电刺激膈神经所得的远端运动潜伏期之差 ,并与 31例 6 1侧正常对照者的结果对比。结果 IDP患者较对照者膈神经根传导时间延长 ;膈神经根传导时间异常与临床呼吸困难相关 ;膈神经根传导时间的异常率高于临床呼吸困难出现率。结论 膈神经根传导时间能从电生理水平反映IDP患者与呼吸有关的脊神经根功能状态 ,与临床呼吸困难密切相关。

Objective To investigate the features and application of phrenic radix conduction time(PRCT) in inflammatory demyelinating polyneuropathy(IDP) patients Methods Distal motor latency(DML) was recorded by stimulating phrenic nerve electrically and phrenic nerve root magnetically in 20 IDP patients with surface electrodes at intercostal space The difference of the two DML was calculated and compared with those recorded previously from 61 sides in 31 healthy control subjects Results PRCT of the IDP patients was longer than that of the controls, and it correlated with the severity of clinical dyspnea The abnormal rate of PRCT was higher than the incidence of clinical dyspnea Conclusions PRCT could reflect the functional status of the spinal roots related to respiration in IDP patients at an electrophysiological level It correlates well with the degree of clinical dyspnea Its detection is helpful to find out the subclinical dyspnea in IDP patients