期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

急性冠状动脉综合征患者血清C-反应蛋白的临床意义 被引量：1

Clinical Significance of Serum C-reactive Protein(CRP) in Patients with Acute Coronary Syndrome
下载PDF
导出
摘要 目的 :探讨急性冠状动脉综合征 (ACS)患者血清C_反应蛋白 (CRP)的改变及其与冠状动脉粥样斑块稳定性的关系。方法 :用散射光比浊法测定65例ACS患者及50例对照组血清CRP含量 ,ACS组均行冠状动脉造影 (CAG)及血管内超声 (IVUS)检查 ,根据冠状动脉病变在血管内超声显像上的管壁横断面分布将ACS组又分为ACS1(同心性斑块 )和ACS2(偏心性斑块或血栓形成 )。结果 :ACS组CRP水平明显高于对照组 (P<0.01) ,ACS2组CRP水平明显高于ACS1组 (P<0.05)。结论 :炎症反应在ACS发病中起重要作用 。 Objective:To study the serum level of C_reactive protein(CRP)in patients with acute coronary syndrome(ACS)and the relationship between CRP and the stability of coronary artherosclerosis plaque.Methods:Serum levels of CRP in 65 patients in ACS group were examined with coronary angiography(CAG)and intravascular ultrasound(IVUS).Results:The level of CRP in ACS group was significantly higher than that in control group(P<0.01).The level of GRP in ACS 2 group(eccentric plaque and/or thrombosis)was higher than that in ACS1 group(concentric plaque).Conclusion:Inflammation has an important effect in the development of ACS,CRP is relative to unstable lesion of plaque.
作者 陈欣 郭素箴 党群 曹燕然
机构地区 天津市第一中心医院心内科
出处 《天津医药》 CAS 北大核心 2003年第2期88-89,共2页 Tianjin Medical Journal
关键词 急性冠状动脉综合征 临床意义 C反应蛋白质 C_reactive protein coronary disease acute disease syndrome
分类号 R543.3 [医药卫生—心血管疾病]
  • 相关文献

参考文献8

  • 1Oltrona L, Ardissino D, Merlini PA, et al.C-reactive protein elevation and early outcome in patients with unstable angina pectoris. Am J Cardiol, 1997, 80:1002～ 6.
  • 2RidKer PM, Glynn RJ, Hennekens CH. C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation, 1998, 97:2007～ 11.
  • 3Torzewski J, Torzewski M, Bowyer DE, et al. C-reactive protein frequently colocalizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries. Arterioscler Thomb Vasc Biol, 1998, 18:1386～ 92.
  • 4Reynolds GD, Vance RP. C-reactive protein immunohistochemical localization in normal and atherosclerotic human aortas. Arch Pathol Lab Med, 1987, 111: 265～ 9.
  • 5Mendall MA, Patel P, Ballam L, et al. C-reactive protein and its relation to cardiovascular risk factor: a population based cross sectional study.BMJ, 1996, 312: 1061～ 5.
  • 6Ridker PM, Cushman M, Stampfer MJ, et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med, 1997, 336:973～9,
  • 7Anderson JL, Carlquist JF, Muhlestien JB, et al. Evaluation of C-reactive protein, an inflammatory marker, and infections serology as risk factors for coronary artery disease and myocardial infarction. J Am Coll Cardiol, 1998, 32: 35～ 41.
  • 8Rdiker PM, Cushman M, Stampfer MJ, et al. Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation, 1998, 97: 425～ 8.

同被引文献5

  • 1内科学.叶任高主编(第5版)[M].北京:人民卫生出版社,2001.550.
  • 2Jurlandeer B, Clemmensen P, Ohman EM, et al. Serum myoglobin for the early non-invasive detection of coronary reperfusion in patients with acute myocardial infarction[J].Eur Heart J,1996,17(3):399 ～406.
  • 3Apple FS, Christenson RH, Valders R, et al. Simutaneous rapid measurement of whole blood myoglobin,creatine kinase MB and cardiac troponin I by the triage cardiac panner for detection of myocardial infarction[J] .Clin Chem, 1999,45(2): 199 ～ 205.
  • 4刘小平.血清CK、TnI、CRP测定对急性心肌梗死诊断价值[J].上海免疫学杂志,2000,20(2):100-100.
  • 5Alexander R W. Inflammation and coronary artery disease [ J ]. N Engl J Med, 1994, 331(7) :468 - 469.
天津医药
2003年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部