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胸腺素α1的研究进展 被引量:3

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作者 匡燕
出处 《西南国防医药》 CAS 2003年第1期99-101,共3页 Medical Journal of National Defending Forces in Southwest China
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  • 1曾民德,茅益民,姚光弼,周霞秋,王豪,徐道振,姚集鲁,侯金林,王宇明,任红,陈亚岗,牛俊奇,王耀宗.阿德福韦酯治疗HBeAg阳性的中国慢性乙型病毒性肝炎患者52周的多中心临床研究[J].中华传染病杂志,2005,23(6):387-394. 被引量:164
  • 2张雪霞,陈劲春.重组人干扰素α_(2a)和胸腺肽α_1融合蛋白的分子设计及其基因表达产物的鉴定[J].北京化工大学学报(自然科学版),2006,33(1):23-26. 被引量:8
  • 3Goldstein A L,Low TL,Mc Adoom,et al.Thymosin alpha1:isolation and sequence analysis of an immunologically active thymic polypeptide[J]. Natl A Cad Sci, 1977,74:725-729.
  • 4Naylor PH, Friedman-Kien A, Hersh E,et al. Thymosin alpha1 and thymosin beta 4 in serum: comparison of normal,cord,homosexual and AIDS serum[J]. Int J Immunopharmacol, 1986, 8(7) :667-676.
  • 5Knutsen AP, Freeman J J, Mueller KR, et al. Thymosin-alpha1 stimulates maturation of CD34^+ stem ceils into CD3^+、CD4^+ cells in an in vitro thymic epithelia organ coculture model [J]. Int J Immunopharmacol, 1999,21:15.
  • 6Baumann CA,Badamchian M,Goldsteln AL.Tα1 antagonizes induced apoptosis of developing thymocytes in vitro[J]. Mol Cell Biol, 1995,6S:356.
  • 7Baumann CA, Badamchian M, Goldstein AL.Thymosin alpha( 1 )is a time and dose-dependent antagonist of dexamethasone-induced apeptosis of routine thymocytes in vitro [J]. Int J Immunopharmacol,2000,22:1057- 1066.
  • 8Roy R,Singh SM, Shanker A. Mechanism of thymocyte apoptosis induced by serum of tumor-bearing host: the molecular events involved and their inhibition by thymosin alphal-1[J]. Int J Immunopharmacol,2000,22: 309-321.
  • 9Beuth J, Schierholz JM, Mayer G. Thymosin alpha (1)application augments ummune response and down-regulates tumor weight and organ colonization in BALB/c-mice[J]. Cancer Lett, 2000,159: 9-13.
  • 10Silecchia G,Guamo E,Sinlbaldi-Vallebona P,et al. Efficacy of repeated cycles of chemo-immunotherapy with thymosin alpha1 and interleukin -2 after intraperitoneal 5-fluorouracil delivery [J]. Cancer Immunol Immunother, 1999,48:172-178.

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