摘要
目的探讨灭多威染毒家兔周围神经功能的变化。方法 以25 mg/kg的灭多威对家兔进行皮肤染毒30min,测定染毒前后家兔前肢与后肢运动神经的远端及近端潜伏时、传导速度以及骨骼肌肌电图变化。结果与对照组及染毒前比较,前后肢运动神经远端、近端潜伏时明显延长,传导速度明显减慢(P<0.05,P<0.01),骨骼肌肌电图出现大量纤颤波和正锐波。结论灭多威染毒对家兔周围神经功能有影响。
Objective In order to explore the effect of methomyl exposure on peripheral nervous function in rabbits. Methods Disal latent period (DLP) , proximal latent period (PLP) and nervous conducdon velocity (NCV) of the motor nerves and electromyo-gram of skeletal muscles were measured in rabbits exposed to methomyl for 30 min. Results Compared with those in control and pre-ex-posure groups DLP and PLP appeared to be prolonged, NCV and electromyogram of skeletal muscles significantly decreased ( P < 0.05, P < 0.01) , the latter also showed abnormal change. Conclusion It suggested that acute methomyl treatment might damage certain function of peripheral nerve system in rabbits.
出处
《中国职业医学》
CAS
北大核心
2003年第1期25-26,共2页
China Occupational Medicine
关键词
灭多威中毒
周围神经
家兔
Methomyl
Peripheral nerve system
Rabbits
