^(18)F-FDGPET显像在肺癌治疗效果评价中的意义

Clinical value of ^(18) F-FDG PET imaging in assessing therapeutic effect for lung cancer

目的:探讨18F标记的脱氧葡萄糖(18F-FDG)正电子发射型计算机断层显像(PET)在肺癌治疗中对肺癌放化疗效果的价值。方法:对22例肺癌患者在放化疗前后进行18F-FDGPET显像,观察肺部病灶治疗前后图像和标准化摄取值(SUV)的变化,并进行临床随访观察。结果:治疗结果,显效6例,有效9例,无效4例,进展3例;随访观察与PET显像结果一致。结论:18F-FDGPET显像能及时反映肺癌放化疗效果,对治疗有指导价值。

Objective:To assess the result of radiotherapy and chemotherapy in the treatment of lung cancer with 18 F-FDG PET imaging.Meth ods :18 F-FDG PET imagings were performed in22patients with lung cancer before and after radio-therapy and chemotherapy.PET images and standardized uptake value(SUV)of lung focus were observed and detected,and clinical follow-up survey was made.Results:Six cases with primary focus disappeared,9cases with decremental SUV more than10%,4cases with decremental SUV less than10%or incremental SUV less than10%,and3cases with incremental SUV more than or equal to10%.Results of PET imaging and follow-up survey showed no difference.Conclusion:18 F-FDG PET imaging can be used to assess the effect of radiotherapy and chemotherapy in lung cancer and provide a guide to therapy.