山羊痘苗对羊口疮的交叉免疫试验

Cross-Immunity Test on Orf Using Attenuated Live Goat Pox Vaccine

在天祝种羊场对羔羊、怀孕母羊共2,189只,用山羊痘苗进行了羊口疮(Orf)交叉免疫试验。通过观察发病率和攻毒试验来确定免疫效果。山羊痘苗一次免疫组羔羊可抵抗1个MID/0.05ml的Orf病毒攻击,三次免疫组羔羊可抵抗10个MID/0.05ml的病毒攻击。山羊痘苗免疫组羔羊发病率比同期平均发病率可降低50％。对临产前一个月的怀孕母羊用山羊痘苗免疫,可保护所产羔羊在哺乳期不发生本病。

Cross-immunity test on Orf using attenuated live goat pox vaccine was carried out in 2,189 lambs and ewes on Tianzhu Breeder sheep farm.The immune effect was evaluated by incidence and challenge.The results showed that the lambs vaccinated once with the goat pox vaccine could resist against challenge with 1 MID/0.05ml of Orf virus,and those vaccinated thrice with the vaccine could resist to 10 MID/0.05ml of Orf virus.The incidence of orf in the lambs vaccinated with the goat pox vaccine was reduced to 50% of the average incidence.Ewes were vaccinated with the vaccine one month before lamting,and the lambs produced by the ewes did not infect Orf in suckling period.