变应性鼻炎患者血清及鼻分泌物中屋尘螨粉尘螨sIgE相关性研究

Relationship between Dermatophagoides pteronyssinus and Dermatophagoides farinae sIgE in serum and local secretion of perennial allergic rhinitis patients

目的 :探讨常年性变应性鼻炎患者血清及鼻分泌物中屋尘螨、粉尘螨sIgE含量的相关性。 方法 :收集常年性变应性鼻炎患者血清及鼻分泌物 ,测定其中屋尘螨、粉尘螨sIgE ,然后进行分析。 结果 :血清及鼻分泌物中屋尘螨、粉尘螨sIgE浓度基本相等 ,其浓度及自然对数值间具有良好的相关性 (相关系数均大于 0 .97)。结论 :两种螨sIgE在过敏患者体内含量的高度一致性 。

Objective:To investigate the relationship between Dermatophagoides pteronyssinus(Dp) and Dermatophagoides farinae(Df) specific IgE in the serum or local secretion of perennial allergic rhinitis (PAR) patients. Method:The serum and nasal secretion of suspected PAR patients were collected, then the concentration of mite sIgE in them were measured and analyzed. Result:The concentration of Dp and Df in serum or the local secretion was almost the same. The relationship between the two mite sIgE concentration and logarithm is good both in the serum or the local secretion(relative coefficient is about 0.97 ). Conclusion:The sIgE amount of the two mite is very similar in the body of the suspected AR patients, so only one kind of sIgE is needed to be measured to reflect the allergic situation in clinic.