经阴道彩色多普勒超声对不孕症患者治疗前后子宫、卵巢动脉血流变化的研究

Study on Uterine and Ovarian Blood Flow by Transvaginal Color Doppler Flow Imaging in Infertile Women Before and After Treatment with Clomiphene and hCG

目的探讨经阴道彩色多普勒超声 (TV CDFI)在无排卵周期不孕症治疗上的应用价值。方法采用TV CDFI检测 5 6例无排卵周期不孕症患者经克罗米芬及绒毛膜促性腺激素 (hCG)治疗前后子宫、卵巢动脉的血流变化。结果无排卵周期不孕症患者治疗前子宫、卵巢动脉在月经的不同时期收缩期峰值速度(PSV)与阻力指数 (RI)均差异无显著性 (P >0 .0 5 )。治疗后卵巢动脉恢复了周期性变化 ,且优势侧卵巢动脉RI显著低于对侧 (P <0 .0 5 )。结论通过检测子宫、卵巢动脉血流阻力的动态变化 ,不仅可判断药物对不孕症患者的疗效 。

ObjectivesTo evaluate the application of transvaginal color Doppler flow imaging(TV CDFI) in treatment of infertile women with ovulatory dysfunction. Methods Before and after treatment with clomiphene and human chorionic gonadotropin (hCG), the changes of blood flow in uterine and ovarian arteries of 56 patients with anovulatory infertility were detected by TV CDFI .Results There was no statistically significant difference in either peak systolic velocity ( PSV ) or resistance index ( RI ) of blood flow within uterine and ovarian arteries of the patients with anovulatory infertility during different periods of their menstrual cycle before treatment (P>0.05 ).After treatment, blood flow in uterine and ovarian arteries restored cyclic changes. The RI in ovarian arteries of predominant side were significantly lower than that of the contralateral side (P<0.05 ).Conclusion To detect the dynamic changes of blood flow resistance in uterine and ovarian arteries not only can assess the therapeutic efficacy of drugs for patients with anovulatory infertilily, but also can predict ovulation and find out the causes of infertility.