微电刺激治疗舍格伦综合征临床研究

A clinical study on the treament of Sjogren's syndrome with electrical stimulation

目的 :观察微电刺激治疗舍格伦综合征 (SS)临床效果。方法 :应用微电刺激治疗舍格伦综合征10例。治疗前后用改良的治疗意外症状量表 (TESS量表 )评价口干症状 ,并测定唾液动、静态总流率。结果 :SS经微电刺激治疗后口干症状明显改善 2例 ,中度改善 2例 ,稍有改善 5例 ,无效 1例。动、静态唾液总流率无明显变化。结论 :微电刺激短期治疗舍格伦综合征 ,口干症状明显改善 。

objective: To investigate the effect of electrical stimulation on the treament of Sjogren's syndrom(SS) . Methods: Ten SS patients were treated with electrical stimulation at less than 6 V and 9 mA of the current for 6 min each time and three times each day, the treatment was countinued for 20 days. The symptom of dry mouth was classified into 0,1,2,3 and 4 according to a treatment emergent symptom scale (TESS). Unstimulated and stimulated whole saliva flow rates on chewing medical paraffin were determined before and after treatment.Results: The symptom of dry mouth was markedly improved in two SS patients, moderately in 2 and slightly in 5. No improvement was found in 1 case. Before and 1, 2 and 3 weeks after treatment unstimulated whole saliva flow rate(ml/min) was 0.14±0.35, 0.14±0.38, 0.16 ±0.35 and 0.22±0.42; stimulated 0.58±0.40, 0.61±0.41, 0.78±0.37 and 0.90±0.39, respectively.Conclusion: Electrical stimulation can markedly improve the symptom of dry mouth in the patients with SS.