4-硝基邻苯二腈的合成

The Synthesis of 4-nitrophthalonitrile

以4-硝基邻苯二甲酰亚胺为原料,经氨化、脱水反应合成了4-硝基邻苯二腈。对4-硝基邻苯二甲酰亚胺的氨化和4-硝基邻苯二甲酰胺的脱水反应条件进行了研究,获得较佳的工艺条件,从而制得了高纯度的4-硝基邻苯二腈,总收率达59 3%,纯度达99 5%。

The 4-nitrophthalonitrile was prepared by amination and dehydration with 4-nitrophthalimide. To prepare high pure 4-nitrophthalonitrile, we have studied of the reaction conditions of the amination of 4-nitrophthalimide and the dehydration of 4-nitrophthalamide. The yield of 4-nitrophthalonitrile reached above 59%,the product with purity of more than 99% was obtained.