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肥厚型心肌病的MR首过心肌灌注初步研究 被引量:6

Preliminary Study of Magnetic Resonance First-Pass Myocardial Perfusion Imaging in Hypertrophic Cardiomyopathy
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摘要 目的 评价心肌首过灌注磁共振成像技术对肥厚型心肌病 (HCM )心肌缺血的诊断作用。方法 对 2 1例肥厚型心肌病患者 ,行MR心脏形态学及功能学检查 ,并进行MR心肌灌注检查 ,随后对心肌灌注参数进行分析 ,同时对比分析心功能变化。结果 局部心肌最大信号强度增加值 (SIm)减低 9例 ,其中合并心内膜下缺血 3例 ;灌注阳性组与阴性组相比较 ,左室短轴缩短率及局部室壁增厚率明显下降。结论 MR心肌首过灌注成像能够准确地判断肥厚型心肌病的缺血改变 ,磁共振成像技术可以多方面对肥厚型心肌病进行评价。 Objective To access the diagnostic value of magnetic resonance first pass perfusion imaging in hypertrophic cardiomyopathy (HCM) with myocardial ischemia. Methods Twenty one patients with HCM were studied with gadolinium enhanced ultrafast,magnetic resonance first pass imaging and cine MRI. The parameter related to perfusion and the function information were analyzed and compared statistically. Results Maximal signial intensity increase (SIm) of 9 patients were lower; subendocardial ischemia in 3 patients was observed. Patients with a positive result showed lower left ventricular fractional shortening [(34.3±8.5)% vs (41.6±7.2)%, P < 0.05] and left ventricular wall thicking [(21.4±5.3)% vs ( 27.9 ±7.1)%, P <0.05] than those of patients with a negative result. Conclusion Magnetic resonance first pass perfusion imaging has high sensitivity in judging myocardial ischemia. MRI may be the most useful method to evaluate HCM.
出处 《中国医学影像技术》 CSCD 2003年第2期170-171,共2页 Chinese Journal of Medical Imaging Technology
关键词 肥厚型心肌病 灌注 磁共振成像 心肌缺血 诊断 Hypertrophic cardiomyopathy Perfusion Magnetic resonance imaging
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