N-烃氧丙酰基四氢噻唑-2-硫酮的合成

Synthesis of N-Alkoxypropionyl-1,3-thiazolidine-2-thiones

在三聚氯氰存在下由烃氧丙酸与四氢噻唑-2-硫酮反应得到N-烃氧丙酰四氢噻哇-2-硫酮(2a-i),由2a,c-h与格氏试剂反应得到烃氧乙基苯基酮(3a,c-h).产物2a-i未见报道.

3-Alkoxypropionyl-l,3-thiazolidine-2-thiones 2a-i were synthesized from 3-alkoxy-propionic acid and 1, 3-thiazolidine-2-thione by using cyanuric chloride as the condensing agent. Alkoxyethylphenyl ketones 3a,c-h were obtained by treatment of 2a,c-h with phenylmagnesium bromide 2a-i are new compounds.