藏药蓝翠雀花中的新二萜生物碱

A New Diterpenoid Alkaloid from Delphinium Caeruleum

<正> 蓝翠雀花(Delphinium caeruleum Jacq.ex Camb.)~[1]在甘肃西南部、西藏、青海等地分布较广,藏民常用其治疗牙痛、跌打损伤.其化学成分迄今未见报道.我们将其全草用乙醇浸泡,石油醚脱脂,乙醚除去色素,酸碱常法处理,氯仿萃取得总生物碱.用氧化铝、硅胶进行多次柱层析及硅胶薄层制备层析,分得碱(1)～(4).

A new minor diterpenoid alkaloid,caeruline(1),was isolated from Delphinium,caeruleum Jacq.ex Camb.Its structure was elucidated on the basis of spectral analysis.Along with this new compound,three known diterpenoid alkaloids(tatsiensine,delcosine and lycocto-nine)were also isolated.They have not been isolated in this plant previously.