改进的微悬浮聚合法制备聚合物微球

Preparation of Polymeric Microparticles by Improved Microsuspension Polymerization

<正> 微悬浮聚合法是制备聚合物微球的方法之一,它是先将单体相分散为一定粒度的微液滴,再在低速搅拌(75～100r/min)下进行聚合反应~[1,2],对聚合设备无特殊要求,且避免了悬浮聚合法制备微球时连续数小时的高速搅拌~[3],只要有合适的均化器即可大批量制备1～50μm的聚合物微球,且可适当控制粒度.但由于一般单体在分散介质中均有一定的溶解性,且液滴粒径越小单体溶解度越大。

The present paper represents the improved microsuspension polymerization for the preparation of polymeric microparticles.The effects of several factors on the stability of the system were studied.The results show that it could be carried out in a wide range of reaction conditions.The method may be applied to batch production of polymeric microparticles.