含酯基聚合物液相色谱填料的制备与性能

Preparation and Characterization of an Ester-Containing Polymer Packing for High Performance Liquid Chromatography

采用新的聚合工艺制备了用于高效液相色谱的双甲基丙烯酸乙二醇酯-苯乙烯-二乙烯苯共聚物柱填料.该球形聚合物的料径为5±2μm,测定了渗透性、理论塔板高度和选择性等柱参数,并与文献中类似填料的数据作比较.此种含酯基聚合物柱效较高、刚性好、渗透性强,适于分离芳胺、酚类和环己酮过氧化物等中等极性混合物.

An ethylene glycol dimethylacrylate-styrene-divinylbenzene copolymer,used as packing for high performance liquid chromatography was prepared by a novel suspension polymerization process.The spherical particle sizes of the polymer are 5±2 urn.Some column parameters such as the permeability,theoretical plate height and selectivity were determined and compared with the data of similar packings in the literature.It has been found that the ester-containing polymer has not only the higher efficiency but also very good physical properties such as high rigidity and permeability,and that it is suitable for the separation of medium polarity mixtures of aromatic amines,phenols and cyclohex-anone peroxides.